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Drug-free holidays and malaria prevention

October 9th, 2018
We are very pleased to report that our recent research project was published in a very respected journal: Clinical Infectious Diseases (CID).
AND we received this notification in April 2019
As editor-in-chief of Clinical Infectious Diseases and on behalf of the Infectious Diseases Society of America, I would like to thank you for your contribution to our journal in 2018. We are pleased to inform you that your article is in the top 10 percent of the most downloaded articles from the past two years. Congratulations on this outstanding achievement!
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This is a very big deal and speaks to the quality and usefulness of the research. ( and thanks to all the team who helped pull this together! )
Below is the link to the abstract which explains the results nicely.
 This is a big deal as CID is a very respected journal.
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(This was a popular project as it explored a cheaper and easier way to take malaria tablets for trips of less than 4weeks.)
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These are prescription medications.  Don’t forget that all malaria medications are prescription only and need to be discussed with your travel medicine provider.
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 Thank you so much to all our patients who so kindly participated and all the staff who helped pull it together.

2 Responses to “Drug-free holidays and malaria prevention”

  1. Mark Raines says:

    Great to see your published work.

    Intuitively though, how does a tablet with a half life of 20 hrs keep on working a month later? Surely a much smaller daily dose would also be effective, eg the paediatric tablet?

    Do you hand out maxalon at the time for the 25% nausea rates seems pretty impressive.

    Here’s another way to save money

    https://academic.oup.com/jtm/article/23/6/taw064/2751004

    Any thoughts on tafenoquine as another option?

    • Dr Deb says:

      HI Mark
      yes intuitively we do not yet understand why it works.
      There are probably lots of ways to use malarone that will work but the trick is to have the trials and science behind them.
      We don’t use maxolon with malarone as there is an interaction but stemetil is OK. We did find if patients had their dose with a lot of fat – like a pizza – they were more comfortable.
      yes the twice a week regime also seems effective but the feedback I have from travellers is that twice a week is tricky when one is travelling and they ones on our trial were very happy to ‘ get it over and done with’ before the trip.
      Tafenoquine is a really interesting alternative – supplies should be arriving this month
      Regards Dr Deb

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